Biologist II

Responsibilities:

• Plan and execute experiments based on bioanalytical protocol and in vivo study design.
• Analyze pre-clinical in vivo samples based on operational schedule.
• Qualify ligand binding assay based on bioanalysis protocol, interpret result, and make decision on assay readiness.
• Data archiving in ELN and LIMS.
• Effectively communicate experimental plan and results orally and in writing. Contribute to technical report writing and day-to-day lab operations.
• Sample management and sample data QC in LIMS.
• Write, and update experimental protocols and procedures.
• Initiate, design, interpret, troubleshoot operational assay independently and efficiently.
• The LBA Operations Bioanalytical team at ABC QTAS conducts quantitative bioanalysis assays of large molecule therapeutics like mAb, Client, fusion protein and bi-specifics for Pharmacokinetic (PK), Pharmacodynamic (PD) and Toxicokinetic (TK) studies using ligand binding assays to support drug discovery and early development efforts.
• The main responsibilities of a Biologist II involve pre-clinical sample analysis using a ligand binding assay. Sample and reagent management using electronic tools such as Laboratory Information Management System (rLIMS) and others.
• Sample preparation and analysis utilizing hybrid manual and automated systems to generate high quality bioanalytical data. Reporting results to project teams which enable Pharmacokinetic and Pharmacodynamic analysis.

Requirements:

• BS or MS degree in biology, chemistry, or pharmacology.
• 3+ years of pharmaceutical and/or biotechnology industry experience.
• Attention to detail, experience performing lab testing, independent, and self-motivated.
• Ability to properly use common lab tools such as pipettes.
• Ability to operate and maintain laboratory equipment independently.
• Experience with lab automation is highly desirable.
• Experience with ligand binding workflow is required.
• Experience in data driven troubleshooting is highly desirable.
• Proven problem-solving ability.
• Excellent written and verbal communication skills and ability to draft technical reports.
• Proficiency with computers and data analysis software including Excel and LIMS.
• Ability and willingness to work effectively in a highly collaborative and multidisciplinary environment.