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Postdoctoral Research Fellow - Translational Research in Oncology, Mass Spectrometry

Requisition ID: POS000270

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century . Merck's success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world's premier, most research-intensive biopharmaceutical company. Today, we're doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck's leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

Be a part of the legacy: MRL Postdoctoral Research Fellow Program

The Merck Research Laboratories (MRL) Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

As a postdoctoral fellow in Translational Molecular Biomarkers - Mass Spectrometry, you will work with a highly collaborative team of scientists to design, develop and validate a multiplexed immuno-affinity mass spectrometry based assay to simultaneously quantify immune checkpoint and related proteins and apply this assay to clinical studies to investigate the effect of anti-cancer therapies in Merck's oncology pipeline. This work will enable better understandings of the mechanism of action of anti-cancer therapies.

Responsibilities include but are not limited to:

  • Conducting immuno-affinity mass spectrometry on whole blood and PBMC to develop a multiplexed protein quantitation method.
  • Evaluate antibody-based fractionation and isolation of cells.
  • Analysis of samples from clinical studies.
  • Data interpretation, manuscript preparation, publication and presentation of results.
  • Contribute to a safe and compliant laboratory work environment.



Education Minimum Requirement:

  • A PhD with less than (3) years of postdoctoral experience OR graduating with a PhD by summer of 2019.

Required Experience and Skills:

  • Ability to design experiments, inte rpret and track results, and use this information to enable assay development.
  • Skilled in the use of mass spectrometry for the analysis of peptides and proteins.
  • Experience in analysis of biological matrices.
  • Experience in protein separation procedures.

Preferred Experience and Skills:

  • QQQ Quantitative Mass Spectrometry.
  • Immuno-affinity mass spectrometry.
  • Immunology or Oncology research.
  • Biomarkers.

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we're counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we're inventing for life.

If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to

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Job: Post-Doctoral Fellow
Other Locations:
Employee Status: Regular
Travel: No
Number of Openings: 1
Shift (if applicable):
Hazardous Materials:
Company Trade Name: Merck

Nearest Major Market: New York City
Nearest Secondary Market: Newark

Postdoctoral Research Fellow - Translational Research in Oncology, Mass Spectrometry

Kenilworth, NJ
Full Time

Published on 05/02/2019