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Scientist, Biology-Discovery

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.

We are seeking an enthusiastic scientist to join the Cytometric Profiling group and Flow Cytometry/FACS core facility at our Research Laboratories in South San Francisco. Candidates should have experience with flow cytometry theory and practice, especially with BD Biosciences instrumentation. Experience with cell sorting is also highly desired. This position requires the candidate to perform FACS core responsibilities such as daily instrument startup, shutdown, QC, and maintenance. Furthermore, the successful candidate will have good working knowledge of the hardware, fluidics, and optics involved with flow cytometers. In addition to these core activities, the candidate will conduct immunoprofiling of various human, non-human primate, and murine tissues by flow cytometry and/or cell sorting to support team efforts to develop early pipeline immunotherapies. The candidate will work with program team members as well as with other intradepartmental groups to contribute data for regulatory filings of the many new therapeutics entering the clinic. Importantly, this position requires a candidate who has excellent oral and written communication skills and who will enjoy working with a large group of scientists.

Education Minimum Requirement:
"· Minimum of a BS/BA in Biology, Biochemistry, or relevant discipline plus 3-5 years of industry experience or MS/MA in Biology, Biochemistry, or relevant discipline plus 1-2 years of industry experience.

Required Experience and Skills**:
"· Experience with Flow Cytometry, preferably with BD Biosciences flow cytometers and acquisition software (FACS Diva)
"· Data analysis using FlowJo
"· Cell biology or immunology background
"· Excellent communication and interpersonal skills
"· Proficiency with MS Office applications on the Windows operating system
"· Must be able to lift a 20-Liter box of sheath fluid (45 lbs. each)

Preferred Experience and Skills:
"· Cell sorting (FACS)
"· Cell preparation for single cell RNA-sequencing
"· Ex vivo functional assays such as proliferation, phospho-flow, or intracellular cytokine staining
"· New analytical methods such as tSNE, viSNE, CITRUS, FlowSOM, etc.
"· Proficiency with TIBCO Spotfire

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science” and that great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Merck & Co., Inc., Kenilworth, New Jersey, USA is known as "Merck” in the United States, Canada & Puerto Rico. We are known as "MSD” in Europe, Middle East, Africa, Latin America & Asia Pacific. We are a global biopharmaceutical leader with a diverse portfolio of prescription medicines, oncology, vaccines and animal health products.

We are driven by our purpose to develop and deliver innovative products that save and improve lives. With 69,000 employees operating in more than 140 countries, we offer state of the art laboratories, plants and offices that are designed to Inspire our employees as we learn, develop and grow in our careers. We are proud of our 125 years of service to humanity and continue to be one of the world's biggest investors in Research & Development.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.





In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

If you need an accommodation for the application process please email us at

For more information about personal rights under Equal Employment Opportunity, visit:

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We are an equal opportunity employer, Minority/Female/Disability/Veteran - proudly embracing diversity in all of its manifestations.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:


VISA Sponsorship:

Travel Requirements:
No Travel Required

Flexible Work Arrangements:

1st - Day

Valid Driving License:

Hazardous Material(s):
BSL2 Lab

Number of Openings:

Requisition ID:BIO005497

Scientist, Biology-Discovery

South San Francisco, CA
Full Time

Published on 08/19/2019