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Scientist - Discovery Biology, Retinal Diseases

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.

Retinal Diseases Discovery Biology group is seeking a driven and creative Research Associate to join our drug discovery team. This is an exciting opportunity to directly contribute to drug target identification and validation activities in close collaboration with colleagues in Biology, Chemistry and Biologics teams and across our Research & Development Division. The ideal candidate will be an eager-to-learn, self-motivated team player with high-level of scientific curiosity and enthusiasm for drug discovery. The primary responsibilities will include planning and execution of experiments focused on novel target discovery and validation using a wide range of cutting edge in vitro and in vivo techniques. Direct hands-on experience with in vitro and in vivo pre-clinical models of retinal diseases is preferred.

Primary Responsibilities:

  • Design and execute experiments for target identification and validation utilizing in vitro cell-based assays and in vivo disease animal models

  • Employ cutting edge molecular/cell/biochemistry techniques to discover target function and mechanism of action

  • Learn and establish novel platforms and technologies to advance drug discovery efforts


  • B.S. in Molecular Biology, Immunology, Genetics, or related biological discipline and at least 3 years of postgraduate hands-on laboratory experience in academic or industry setting

Required Experience and Skills:

  • Excellent sterile technique and tissue culture experience

  • Ability to independently design, perform, troubleshoot, and interpret biological experiments

  • Proficiency using data analysis and visualization software such as Excel and GraphPad Prism

  • Strong motivation and passion for science

  • Commitment to experimental excellence

  • Excellent oral presentation and communication skills

Preferred Experience and Skills:

  • Hands-on experience handling laboratory animals

  • Knowledge and experience in ocular biology and retinal diseases

  • Hands-on experience with in vitro and in vivo pre-clinical models of retinal diseases

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe. 

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today.


In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

For more information about personal rights under Equal Employment Opportunity, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:




VISA Sponsorship:


Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Work Week


Not Indicated

Valid Driving License:

Hazardous Material(s):

Number of Openings:


Requisition ID:R132229

Scientist - Discovery Biology, Retinal Diseases

South San Francisco, CA
Full Time

Published on 01/18/2022

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