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Senior Scientist - Oligo Bioinformatics

Work Your Magic with us! Start your next chapter and join EMD Serono.

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role:

EMD Serono in Billerica, MA is seeking a Senior Scientist - Oligo Bioinformatics to add to their Oligonucleotide Therapeutics Group (DDTech).

Responsibilities:

  • Utilize Bioinformatics platforms to design, evaluate and optimize siRNA sequences for targeted gene silencing
  • Analyze gene expression data to identify suitable targets for siRNA/ASO development
  • Work closely with chemists and biologists to integrate bioinformatics approaches into experimental workflow
  • Perform transcriptome wide off-target prediction and annotation
  • Develop pipelines that determine mapping coordinates and homology of oligonucleotides to genomes and transcriptomes

Who You Are:

Minimum Qualifications:

  • PhD in Chemistry, Chemical Engineering or other Science or Engineering discipline with 3+ years of direct experience Oligonucleotide field

Preferred Qualifications:

  • Strong scientific curiosity and innovation mindset
  • Proficient in Bioinformatics tools and software (e.g. BLAST, RNA fold, siRNA design tools)
  • Ability to analyze large genomic and transcriptomic datasets including RNA seq, Single cell RNA seq, splice isoforms and variant database
  • Highly collaborative with strong problem-solving ability

Pay Range for this position: $112,800 - $169,200

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

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Senior Scientist - Oligo Bioinformatics

Merck Group
Billerica, MA
Full Time
USD 112,800.00 - 169,200.00 per year

Published on 05/14/2026

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