Vice President, Medical Affairs

Job Title: Vice President, Medical Affairs

Location: Remote (US)

Position Type: Full Time

Reports to: Chief Medical Officer

Company Description:

Latigo Biotherapeutics is a clinical-stage biotechnology company developing novel, non-opioid therapies for the treatment of pain. Our approach is grounded in human biology and focused on targeting the fundamental mechanisms of pain signaling to deliver effective, well-tolerated therapies without the risks associated with opioids. With multiple programs advancing across clinical development, Latigo is committed to transforming the treatment paradigm for patients suffering from acute and chronic pain.

Position Description:

The Vice President, Medical Affairs will establish and lead Latigo's Medical Affairs function, serving as a key strategic partner to the Chief Medical Officer and executive team. This individual will be responsible for shaping and executing the medical strategy across a portfolio spanning a rapidly advancing Phase 3 asset and earlier-stage clinical programs.

This is a highly visible, externally facing role requiring deep scientific and clinical expertise, particularly in pain and neuroscience. The VP will translate Latigo's mechanism-based science and clinical data into a compelling medical narrative, engage thought leaders, and build the foundation for future commercialization. The role requires a leader who can operate strategically while remaining hands-on in a fast-paced, clinical-stage biotechnology environment.

Primary Responsibilities:

• Develop and lead the overall medical strategy aligned with Latigo's clinical development programs and corporate objectives
• Translate clinical and mechanistic data into a clear, differentiated scientific narrative for external stakeholders
• Establish and cultivate relationships with key opinion leaders (KOLs), investigators, and academic experts in pain, neuroscience, and related fields
• Represent Latigo at major medical and scientific congresses, driving awareness of the company's programs and scientific approach
• Lead the development and execution of publication and medical communication strategies, including abstracts, manuscripts, and congress presentations
• Provide strategic medical input into clinical development plans, including trial design, endpoint selection, and interpretation of data
• Partner cross-functionally with Clinical Development, Regulatory, Commercial, and R&D teams to ensure alignment of medical strategy across the organization
• Build and scale the Medical Affairs function, including the phased development of a Medical Science Liaison (MSL) team
• Ensure scientific rigor, compliance, and integrity in all external medical communications and engagements

Qualifications and Requirements:

• MD or PhD required; additional relevant scientific or clinical training is a plus
• Significant experience in Medical Affairs leadership within biotechnology or pharmaceutical industry
• Demonstrated expertise in pain, neuroscience, or related therapeutic areas strongly preferred
• Experience supporting late-stage clinical development and/or preparing for commercialization
• Proven ability to engage and influence external experts and build credibility within the medical community
• Strong track record of scientific communication, including publications and congress presentations
• Experience building or scaling Medical Affairs capabilities in a growing organization preferred

Leadership & Personal Attributes:

• Scientific credibility and intellectual rigor, with the ability to translate complex data into clear insights
• Strategic thinker with the ability to execute in a hands-on, resource-efficient environment
• Strong interpersonal and communication skills, with executive presence and external engagement capabilities
• Collaborative leader who thrives in a cross-functional, fast-paced biotech setting
• High level of integrity, accountability, and commitment to improving patient outcomes

Travel

• This role requires regular travel to major medical conferences, investigator meetings, and external stakeholder engagements.

Why Join Latigo

• This is an opportunity to play a foundational role in building the Medical Affairs function at a company developing a new class of non-opioid pain therapeutics. The VP, Medical Affairs will directly shape how Latigo's science and clinical data are communicated to the medical community and will contribute meaningfully to advancing new treatment options for patients with significant unmet need.